Translational Bioinformatics Senior Group Leader

Emploi Belgique

Titre du poste : Translational Bioinformatics Senior Group Leader

Entreprise : UCB

Description du poste : Make your mark for patientsWe are seeking a talented and experienced Senior Group Leader to join the Translational Bioinformatics group based in Braine, Belgium.About the roleIn this role, you will lead a dynamic and highly motivated team of bioinformatics scientists to generate actionable insights from multi-omic profiling of patient samples and in vitro / in vivo translational models. By helping to better understand the pathways that drive disease, your work will directly support UCB’s neuroscience research portfolio, spanning areas such as epilepsy, neurodegeneration, neuroinflammation.Who you’ll work withA key focus of the role is close integration into project teams, where you will collaborate with multidisciplinary scientists to design, execute, and interpret omic studies, driving the discovery and validation of therapeutic targets and translational research.What you’ll do

• Assist UCB’s therapeutic ambitions in epilepsy, neurodegeneration and neuroinflammation by unlocking mechanistic insight from molecular profiling of patient samples, analysing perturbations of patient-derived cell systems and in vivo / ex vivo disease models, and enriching our knowledge of disease aetiology to inform new targets and drug mechanism of action.
• Provide scientific leadership, mentorship, and guidance to a team of bioinformatics scientists, fostering a collaborative and innovative work environment.
• Advocate seamless collaboration with diverse stakeholders. Driving rapid and iterative refinement of scientific hypotheses to create lasting influence and impact.
• Lead a collaboration with world leading experts in structural epilepsy to identify gene expression changes in specific cell populations that drive disease to inform innovative new therapies
• Embed within therapeutic project teams to align bioinformatics efforts with project objectives. Clearly communicating insights to influence project decision making and translational packages.
• Drive innovation in bioinformatics methods, data visualization, generative and predictive modelling to enhance the impact of data-driven research.
• Stay abreast of advancements in bioinformatics and participate in scientific conferences, ensuring UCB remains at the forefront of the field.

Interested? For this role we’re looking for the following education, experience and skills

• Ph.D. (or equivalent) in Bioinformatics, Computational Biology, Genomics, or related field with 5+ years of industry experience.
• Proven ability to lead and mentor scientists, manage multiple priorities, and foster a collaborative work environment. Ideally in the context of pharm R&D.
• A passion for leveraging bioinformatics to accelerate drug discovery and understanding disease biology, with experience in neurosciences being a major advantage.
• Expertise in multi-omics data processing, analysis, and interpretation, with a strong preference for single cell RNA-seq, spatial transcriptomics and methods for integrating genetic data to ID causal biology.
• Experience in supporting the translation of drug discovery projects into human clinical trials, enabling pre-clinical assessment, biomarker strategies and back translation.
• Exposure to multiple drug modalities including gene therapy would be a plus.
• Experience with HPC, cloud computing platforms, and containerisation technologies (e.g., Docker) for reproducible and portable bioinformatics workflows. Proficiency in programming languages such as R or Python.

If you are interested to learn more about R&D within UCB, please find more information here .RANDATUCBAre you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.

Salaire attendu :

Localisation : Braine-l’Alleud, Brabant Wallon

Date du poste : Fri, 09 May 2025 02:06:56 GMT

Postulez dès maintenant !